Epigenetics and Nuclear Signaling

Epigenetics refers to changes in a chromosome such as DNA methylation and histone modification that affect transcriptional activation and repression, DNA repair, DNA recombination, DNA replication, and chromosome segregation.

Many key proteins such as protein kinases and phosphatases, protein acetyltransferases and deacetylases, protein methyltransferases and demethylases are involved in the regulation of nuclear signaling. Elabscience^® has a wide range of ELISA kits and antibodies for the study associated with Epigenetics & Nuclear Signaling researches.

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Epigenetics &Nuclear Signaling Pathways

P53 Signaling Pathway

P53 is a tumor suppressor protein that regulates the expression of a variety of genes, including apoptosis, growth inhibition, inhibition of cell cycle progression, differentiation and acceleration of DNA repair.

Resources

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