Human FAS/CD95 Antibody Pair Set
E-KAB-0210
Size: | Price: | $499 | |
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Product Information
Background | FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand. |
Synonyms | FASR, TNFRSF6, APO1, APT1, FAS1, FASTM, ALPS1A |
Swissprot | P25445 |
Reactivity | Human |
Usage | Detects Human FAS/CD95 in ELISAs |
Buffer | Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% pro |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Expiration Date | 12 months |