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Beta-TRCP Polyclonal Antibody (E-AB-60396)

AllSizePriceQty
200μL $ 530.00
120μL $ 320.00
60μL $ 200.00
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For research use only.

Verified Samples Verified Samples in IF: HeLa
Dilution IF 1:10-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IF
ClonalityPolyclonal
ImmunogenRecombinant fusion protein of human Beta-TRCP (NP_378663.1).
AbbreBeta-TRCP
SynonymsBETA-TRCP,  BTRC,  Beta-TRCP,  FBW1A,  FBXW1,  FBXW1A,  FWD1,  bTrCP,  bTrCP1,  betaTrCP
Swissprot
Cellular LocalizationCytoplasm. Nucleus.
Concentration1 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAffinity purification
Research AreasCancer,  Cell Biology,  Microbiology,  Neuroscience
ConjugationUnconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
backgroundThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.
Other Clones

1 Results

    Other Formats

    1 Results

    Unconjugated