For research use only. Order now, ship in 3 days
Alternate Names | CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7). |
Abbre | CD4 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG1, κ |
Isotype Control | E-AB-F09792C |
Applications | FCM |
Research Areas | Immunology |
Cellular Localization | Membrane |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | FITC |
Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
Other Clones
1 Results
Other Formats
1 Results
APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
Elab Fluor®Violet 450
Elab Fluor®Violet 500
Elab Fluor®Violet 540
Elab Fluor®Violet 610
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP
PerCP/Cyanine 5.5
Unconjugated
- Effect of pectoral nerve block type II under general anesthesia on the immune function of patients with breast cancer
IF:2.125
Journal:AMERICAN JOURNAL OF SURGERY(2020)
DOI:10.1016/j.amjsurg.2020.03.008Reactivity:Human
Q1:How to choose the CD4 of different clone numbers?
CD4 [SK3] and CD4 [RM4-5] are used for cytokine testing. On the one hand, because PMA stimulation causes CD4 endocytosis, CD4 clones SK3 and RM4-5 have less effect on endocytosis. On the other hand, the experimental samples for the detection of cytokines need to be fixed, and the CD4 binding domains of SK3 and RM4-5 are less affected by fixators.