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PE Anti-Human IL-17A Antibody[BL168] (E-AB-F1173D)

AllSizePriceQty
100Tests $ 228.00
20Tests $ 90.00
100Tests×2 $ 342.00
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For research use only.

Alternate NamesIL17,  CTLA-8,  CTLA8,  IL 17A
Clone No
Leadtime Order now, ship in 3 days
BackgroundIL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
AbbreIL-17A
Swissprot
HostMouse
ReactivityHuman
ClonalityMonoclonal
Isotype Mouse IgG1, κ
Isotype Control E-AB-F09792D
Applications
ICFCM
Research AreasCell Biology;Immunology;Neuroinflammation;Neuroscience
Cellular Localization
Secreted
FormLiquid
Concentration
5 μL/Test
ConjugationPE
Conjugation InformationPE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12 months
ShippingIce bag
Cat.No. Product Name Sizes
E-CK-A091 Cell Stimulation and Protein Transport Inhibitor Kit 500Assays , 200Assays , 100Assays , 50Assays
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
E-CK-A109 Intracellular Fixation/Permeabilization Buffer Kit 500Assays , 100Assays , 50Assays
Other Clones

1 Results

    Other Formats

    1 Results

    APC

    Biotin

    Elab Fluor®647

    Elab Fluor®700

    Elab Fluor®Violet 450

    FITC

    None (AF/LE)

    PE

    PE/Cyanine 7

    Unconjugated