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Cathepsin L Polyclonal Antibody

Cat.No.:E-AB-13976

Host: Rabbit

Reactivity: H,M

Applications: WB,IHC,ELISA

Summary of Verified Samples

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Western Blot analysis of Mouse kidney and A172 cells using Cathepsin L Polyclonal Antibody at dilution of 1:900.

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Price:   $69
Lead Time:   7~10 days
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Test Application

Verified Samples

Reactivity Application
Human WB
(A172,)

Western Blot analysis of Mouse kidney and A172 cells using Cathepsin L Polyclonal Antibody at dilution of 1:900.

IHC
(brain,thyroid cancer,)

Immunohistochemistry of paraffin-embedded Human brain using Cathepsin L Polyclonal Antibody at dilution of 1:40.

Immunohistochemistry of paraffin-embedded Human thyroid cancer using Cathepsin L Polyclonal Antibody at dilution of 1:40.

Mouse WB
(kidney,)

Western Blot analysis of Mouse kidney and A172 cells using Cathepsin L Polyclonal Antibody at dilution of 1:900.

Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Related Reagents

Application Products
WB Western Blot Detection Kit(E-IR-R304)
IHC 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)(E-IR-R217)

Product Details

Clonality Polyclonal
Isotype IgG
Concentration 0.5 mg/mL
Storage Store at -20℃. Avoid freeze / thaw cycles.
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer, Neuroscience, Signal Transduction
Conjugation Unconjugated
Cellular cellular_localization Lysosome.

Immunogen Details

Immunogen Recombinant protein of human CTSL
Abbre CTSL
Synonyms cathepsin L,1 b,Cathepsin L1,Cathepsin L1 light chain,CathepsinL,CATL,CATL1,cb15,CTSL,CTSL1,ctsl1b,FLJ31037,hgg1,Major excreted protein,MEP,MGC123162,wu:fb30g09
Swissprot P07711
Gene Accession BC012612
Calculated MW 38kDa

Background

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.
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