Cathepsin L Polyclonal Antibody
Cat.No.:E-AB-13976
Host: Rabbit
Reactivity: H,M
Applications: WB,IHC,ELISA
Summary of Verified SamplesWestern Blot analysis of Mouse kidney and A172 cells using Cathepsin L Polyclonal Antibody at dilution of 1:900.
Immunohistochemistry of paraffin-embedded Human brain using Cathepsin L Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of paraffin-embedded Human thyroid cancer using Cathepsin L Polyclonal Antibody at dilution of 1:40.
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| Price: | $69 |
Test Application
Verified Samples
| Reactivity | Application |
| Human | WB (A172,)  Western Blot analysis of Mouse kidney and A172 cells using Cathepsin L Polyclonal Antibody at dilution of 1:900. (brain,thyroid cancer,)   Immunohistochemistry of paraffin-embedded Human brain using Cathepsin L Polyclonal Antibody at dilution of 1:40. Immunohistochemistry of paraffin-embedded Human thyroid cancer using Cathepsin L Polyclonal Antibody at dilution of 1:40. |
| Mouse |
WB (kidney,) Western Blot analysis of Mouse kidney and A172 cells using Cathepsin L Polyclonal Antibody at dilution of 1:900. |
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Related Reagents
| Application | Products |
| WB | Western Blot Detection Kit(E-IR-R304) |
| IHC | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)(E-IR-R217) |
Product Details
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 0.5 mg/mL |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Cellular cellular_localization | Lysosome. |
Immunogen Details
| Immunogen | Recombinant protein of human CTSL |
| Abbre | CTSL |
| Synonyms | cathepsin L,1 b,Cathepsin L1,Cathepsin L1 light chain,CathepsinL,CATL,CATL1,cb15,CTSL,CTSL1,ctsl1b,FLJ31037,hgg1,Major excreted protein,MEP,MGC123162,wu:fb30g09 |
| Swissprot | P07711 |
| Gene Accession | BC012612 |
| Calculated MW | 38kDa |
Background
| The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. |