Added to cart successfully !

Cathepsin B Polyclonal Antibody

Cat.No.:E-AB-13973

Host: Rabbit

Reactivity: H,M,R

Applications: IHC,ELISA

Summary of Verified Samples

Filter:

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using Cathepsin B Polyclonal Antibody at dilution 1:35.

Immunohistochemistry of paraffin-embedded Human liver using Cathepsin B Polyclonal Antibody at dilution of 1:100(Elabscience Product Detected by Lifespan).

Size:  
Qty:
- +
Price:   $69
Lead Time:   7~10 days
Add to cart

Test Application

Verified Samples

Reactivity Application
Human IHC
(lung cancer,liver,)

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using Cathepsin B Polyclonal Antibody at dilution 1:35.

Immunohistochemistry of paraffin-embedded Human liver using Cathepsin B Polyclonal Antibody at dilution of 1:100(Elabscience Product Detected by Lifespan).

Dilution

IHC 1:50-1:100

Related Reagents

Application Products
WB Western Blot Detection Kit(E-IR-R304)
IHC 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)(E-IR-R217)

Product Details

Clonality Polyclonal
Isotype IgG
Concentration 0.3 mg/mL
Storage Store at -20℃. Avoid freeze / thaw cycles.
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer, Neuroscience, Signal Transduction
Conjugation Unconjugated
Cellular cellular_localization Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Immunogen Details

Immunogen Recombinant protein of human CTSB
Abbre CTSB
Synonyms Amyloid precursor protein secretase,APP secretase,APPS,CATB,Cathepsin B heavy chain,Cathepsin B1,CathepsinB,CPSB,CTSB,cysteine protease,OTTHUMP00000116009,OTTHUMP00000229510,OTTHUMP00000229511,OTTHUMP00000229512,OTTHUMP00000229514,OTTHUMP00000229515,OTTHUMP00000229516,Preprocathepsin B
Swissprot P07858
Gene Accession BC010240

Background

The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
If you have any question about the product, please feel free to contact us or leave a message