Tools for SARS-CoV-2

In late December 2019, a new virulent virus emerged that produced a potentially fatal atypical pneumonia, eventually called COVID-19. Identification and sequencing of the virus responsible for this outbreak determined that it was a novel coronavirus (CoV), which was termed SARS-CoV-2 (2019-nCoV, COVID-19 virus).

With the now global outbreak of COVID-19, SARS-CoV-2 early diagnostics and infection prevention and control has become critical. Elabscience^® can provide the following products lines for SARS-CoV-2 (2019-nCoV, COVID-19 virus) research:

Essential Reagents for COVID-19(SARS-CoV-2) IgM/IgG Rapid Test Development

Elabscience^® provides essential reagents for development of COVID-19 IgG/IgM Lateral Flow (Rapid Test) assay to help with the qualitative detection of IgG and IgM antibodies specific to SARS-CoV-2 in human biological fluids.

Cat. No.	Product Name
E-ELC-RTD001	COVID-19 IgG/IgM Rapid Test Development Kit
E-ELC-RTD002	COVID-19 IgG/IgM Rapid Test Development Kit(No colloidal gold conjugated)
E-ELC-001	Recombinant SARS-Cov-2 N Protein (His Tag)
E-ELC-002	Recombinant SARS-CoV-2 N Protein (with colloidal gold conjugated)
E-ELC-003	Mouse anti-human IgG monoclonal
E-ELC-004	Mouse anti-human IgM monoclonal
E-ELC-005	Goat anti-chicken IgY polyclonal
E-ELC-006	Chicken IgY(with colloidal gold conjugated)
E-ELC-008	Buffer for Rapid Test Development(02)
E-ELC-09	Chicken IgY

10 Minutes Rapid Detection of COVID-19 (SARS-CoV-2) IgM/IgG (GICA)

This kit is a lateral flow devices for the qualitative detection of IgG and IgM antibodies to the coronavirus in human whole blood, serum or plasma. It is a rapid chromatographic immunoassayeasy with advantages of easy to use and provide rapid results within 10 minutes.

SARS-CoV-2 Host Associated Proteins

Coronaviruses have four structural proteins (E,M,N,S protein) that can bind to membrane receptors on host cells, thereby mediating the fusion of the virus and the cell membrane. After the S protein of SARS-CoV-2 interacts with ACE2 and then enters the cell through endocytosis, Cathepsin B/L degrades the Spike protein to release nucleic acids of virus. In addition, CD147 also plays a functional role in promoting SARS-CoV-2 invasion into host cells.

Cat. No.	Product Name	Purity	Accession
PKSH032068	Recombinant Human ACE2 Protein (His Tag)	> 95 %	Q9BYF1
PKSH032179	Recombinant Human Cathepsin B/CTSB Protein (His Tag)	> 95 %	P07858
PKSM040956	Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)	> 95 %	P10605
PKSH032182	Recombinant Human Cathepsin L/CTSL Protein (His Tag)	> 95 %	P07711
PKSM041247	Recombinant Mouse Cathepsin L/CTSL Protein (aa 18-334, His Tag)	> 95 %	P06797
PKSH032377	Recombinant Human CD147/Basigin Protein (His Tag)	> 95 %	P35613-2
PKSM041223	Recombinant Mouse CD147/Basigin Protein (His Tag)	> 90 %	NP_001070652.1

ELISA Kits for SARS-CoV-2 Antigen/Antibody Detection

Elabscience^® newly developed ELISA kits for SARS-CoV-2 antigen/antibody determination. These kits are mainly specific to the most important structural proteins, the spike protein and nucleocapsid protein.

Application	Target	Cat.NO.	Product Name
COVID-19 Antibody Qualitative Determination	N protein	E-EL-E600	SARS-CoV-2 Nucleocapsid Protein IgG ELISA Kit
		E-EL-E601	SARS-CoV-2 Nucleocapsid Protein IgM ELISA Kit
		E-EL-E606	SARS-CoV-2 Neutralization Antibody ELISA Kit
	S protein	E-EL-E602	SARS-CoV-2 Spike Protein IgG ELISA Kit
		E-EL-E603	SARS-CoV-2 Spike Protein IgM ELISA Kit
		E-EL-E607	SARS-CoV-2 Spike Protein Total Antibody ELISA Kit
COVID-19 Antigen Quantitative Determination	N protein	E-EL-E604	SARS-CoV-2 Nucleocapsid Protein ELISA Kit
COVID-19 Antigen Quantitative Determination	S protein	E-EL-E605	SARS-CoV-2 Spike Protein S1 RBD ELISA Kit

ELISA Kits for Monitoring the Cytokine Storm

Accumulating research evidence indicates that many patients with severe COVID-19 might have a cytokine storm syndrome, and this suggests that people with severe COVID-19 or suspicious COVID-19 infection should be monitored for hyperinflammation.

Cat. No.	Target	Reactivity
E-EL-H0102	IL-6	Human
E-EL-H6008	IL-8	Human
E-EL-H0149	IL-1β	Human
E-EL-H0109	TNFα	Human
E-EL-H0108	IFNγ	Human
E-EL-H6005	MCP1	Human
E-EL-0162	TGF-β1	Universal
E-EL-H0043	CRP	Human

SARS-CoV-2(2019-nCoV) Antibodies

Since the SARS-CoV2-Spike protein and Nucleocapsid Protein (NP) are the biomarkers of 2019-nCoV, and angiotensin convertenzyme2 (ACE-2) is the main surface receptor to SARS-CoV2 , it is important to fully understand the role these proteins play in SARS-CoV-2 infection. Elabsicnece^® offers a variety of antibodies to investigate the mechanisms of the SARS-CoV-2 life cycle.

Molecule	Cat. No.	Product Name
2019-nCoV Spike Neutralizing Antibody	E-AB-V1001	SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV)
	E-AB-V1002	SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV)
	E-AB-V1003	SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV)
	E-AB-V1005	SARS-COV-2 Spike S1 Monoclonal Antibody(2019-nCoV)
	E-AB-V1006	SARS-COV-2 Spike RBD Polyoclonal Antibody(2019-nCoV)
	E-AB-V1007	SARS-COV-2 Spike Monoclonal Antibody(IgG / IgM Positive Control)
	E-AB-V1008	SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV)
	E-AB-V1009	SARS-COV-2 Spike S2 Monoclonal Antibody(2019-nCoV)
	E-AB-V1010	SARS-COV-2 Spike S2 Polyclonal Antibody(2019-nCoV)
2019-nCoV Spike Neutralizing Antibody	E-AB-V1021	Anti-2019-nCoV S-hIgG1 Neutralizing Antibody
	E-AB-V1022	Anti-2019-nCoV S-mIgG1 Neutralizing Antibody
	E-AB-V1023	Anti-2019-nCoV S-cIgG1 Neutralizing Antibody
	E-AB-V1024	Anti-2019-nCoV Spike Neutralizing Antibody
	E-AB-V1025	Anti-2019-nCoV Spike Neutralizing Antibody
	E-AB-V1026	Anti-2019-nCoV S-IgM Neutralizing Antibody
	E-AB-V1027	Anti-2019-nCoV S-IgA Neutralizing Antibody
	E-AB-V1028	Anti-SARS-CoV-2 Spike RBD (CB6 biosimilar) Neutralizing Antibody
2019-nCoV Nucleocapsid Protein Antibody	E-AB-V1011	SARS-COV-2 NP Monoclonal Antibody(2019-nCoV)
	E-AB-V1012	SARS-COV-2 NP ScFv Monoclonal Antibody(2019-nCoV)
	E-AB-V1013	SARS-COV-2 NP Monoclonal Antibody(2019-nCoV)
	E-AB-V1014	SARS-COV-2 NP Monoclonal Antibody(2019-nCoV)
	E-AB-V1015	SARS-COV/SARS-COV-2 NP Polyclonal Antibody(2019-nCoV)
	E-AB-V1016	SARS-COV/SARS-COV-2 NP Polyclonal Antibody(2019-nCoV)
	E-AB-V1017	SARS-COV-2 NP Monclonal Antibody(IgG / IgM Positive Control)
	E-AB-V1018	SARS-COV-2 NP Monoclonal Antibody(2019-nCoV)
ACE2	E-AB-12224	ACE2 Polyclonal Antibody
ACE2	E-AB-70126	ACE2 Polyclonal Antibody
Related Secondary Antibody	E-AB-1001	Goat Anti-Mouse IgG(H+L)(peroxidase/HRP conjugated)
	E-AB-1003	Goat Anti-Rabbit IgG (H+L)(peroxidase/HRP conjugated)
	E-AB-1006	Rabbit Anti-Human IgG(H+L)(peroxidase/HRP conjugated)

Cell Line for the Research of SARS-CoV-2

Current events around the spread of COVID-19 (SARS-CoV-2) and its impact on public health continue to evolve. Researchers all over the world are committed to the development of COVID-19 vaccine and the development of drugs. In vitro experiments using cell lines for drug screening can greatly improve the speed of screening anti-SARS-CoV-2 drugs.

Cell Line	Species
VERO C1008 [Vero E6] cell line	Cercopithecus aethiops
Vero Cell Line	Cercopithecus aethiops
Calu-3 Cell Line	Homo sapiens, Human
HuH-7 Cell Line	Homo sapiens, Human
Caco-2 Cell Line	Homo sapiens, Human
293T [HEK-293T] Cell Line	Homo sapiens, Human
LLC-MK2 cell line	Macaca mulatta, Monkey, Rhesus

Custom Peptides Service

In the researches of coronavirus COVID-19, customized peptides can also be offered. Elabscience offers synthesis service of different quality and purity range.