Tools for SARS-CoV-2
In late December 2019, a new virulent virus emerged that produced a potentially fatal atypical pneumonia, eventually called COVID-19. Identification and sequencing of the virus responsible for this outbreak determined that it was a novel coronavirus (CoV), which was termed SARS-CoV-2 (2019-nCoV, COVID-19 virus).
With the now global outbreak of COVID-19, SARS-CoV-2 early diagnostics and infection prevention and control has become critical. Elabscience® can provide the following products lines for SARS-CoV-2 (2019-nCoV, COVID-19 virus) research:
Essential Reagents for COVID-19(SARS-CoV-2) IgM/IgG Rapid Test Development
Elabscience® provides essential reagents for development of COVID-19 IgG/IgM Lateral Flow (Rapid Test) assay to help with the qualitative detection of IgG and IgM antibodies specific to SARS-CoV-2 in human biological fluids.
10 Minutes Rapid Detection of COVID-19 (SARS-CoV-2) IgM/IgG (GICA)
This kit is a lateral flow devices for the qualitative detection of IgG and IgM antibodies to the coronavirus in human whole blood, serum or plasma. It is a rapid chromatographic immunoassayeasy with advantages of easy to use and provide rapid results within 10 minutes.
SARS-CoV-2 Host Associated Proteins
Coronaviruses have four structural proteins (E,M,N,S protein) that can bind to membrane receptors on host cells, thereby mediating the fusion of the virus and the cell membrane. After the S protein of SARS-CoV-2 interacts with ACE2 and then enters the cell through endocytosis, Cathepsin B/L degrades the Spike protein to release nucleic acids of virus. In addition, CD147 also plays a functional role in promoting SARS-CoV-2 invasion into host cells.
|Cat. No.||Product Name||Purity||Accession|
|PKSH032068||Recombinant Human ACE2 Protein (His Tag)||> 95 %||Q9BYF1|
|PKSH032179||Recombinant Human Cathepsin B/CTSB Protein (His Tag)||> 95 %||P07858|
|PKSM040956||Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)||> 95 %||P10605|
|PKSH032182||Recombinant Human Cathepsin L/CTSL Protein (His Tag)||> 95 %||P07711|
|PKSM041247||Recombinant Mouse Cathepsin L/CTSL Protein (aa 18-334, His Tag)||> 95 %||P06797|
|PKSH032377||Recombinant Human CD147/Basigin Protein (His Tag)||> 95 %||P35613-2|
|PKSM041223||Recombinant Mouse CD147/Basigin Protein (His Tag)||> 90 %||NP_001070652.1|
ELISA Kits for SARS-CoV-2 Antigen/Antibody Detection
Elabscience® newly developed ELISA kits for SARS-CoV-2 antigen/antibody determination. These kits are mainly specific to the most important structural proteins, the spike protein and nucleocapsid protein.
|COVID-19 Antibody Qualitative Determination||N protein||E-EL-E600||SARS-CoV-2 Nucleocapsid Protein IgG ELISA Kit|
|E-EL-E601||SARS-CoV-2 Nucleocapsid Protein IgM ELISA Kit|
|E-EL-E606||SARS-CoV-2 Neutralization Antibody ELISA Kit|
|S protein||E-EL-E602||SARS-CoV-2 Spike Protein IgG ELISA Kit|
|E-EL-E603||SARS-CoV-2 Spike Protein IgM ELISA Kit|
|E-EL-E607||SARS-CoV-2 Spike Protein Total Antibody ELISA Kit|
|COVID-19 Antigen Quantitative Determination||N protein||E-EL-E604||SARS-CoV-2 Nucleocapsid Protein ELISA Kit|
|S protein||E-EL-E605||SARS-CoV-2 Spike Protein S1 RBD ELISA Kit|
ELISA Kits for Monitoring the Cytokine Storm
Accumulating research evidence indicates that many patients with severe COVID-19 might have a cytokine storm syndrome, and this suggests that people with severe COVID-19 or suspicious COVID-19 infection should be monitored for hyperinflammation.
Since the SARS-CoV2-Spike protein and Nucleocapsid Protein (NP) are the biomarkers of 2019-nCoV, and angiotensin convertenzyme2 (ACE-2) is the main surface receptor to SARS-CoV2 , it is important to fully understand the role these proteins play in SARS-CoV-2 infection. Elabsicnece® offers a variety of antibodies to investigate the mechanisms of the SARS-CoV-2 life cycle.
Cell Line for the Research of SARS-CoV-2
Current events around the spread of COVID-19 (SARS-CoV-2) and its impact on public health continue to evolve. Researchers all over the world are committed to the development of COVID-19 vaccine and the development of drugs. In vitro experiments using cell lines for drug screening can greatly improve the speed of screening anti-SARS-CoV-2 drugs.
|VERO C1008 [Vero E6] cell line||Cercopithecus aethiops|
|Vero Cell Line||Cercopithecus aethiops|
|Calu-3 Cell Line||Homo sapiens, Human|
|HuH-7 Cell Line||Homo sapiens, Human|
|Caco-2 Cell Line||Homo sapiens, Human|
|293T [HEK-293T] Cell Line||Homo sapiens, Human|
|LLC-MK2 cell line||Macaca mulatta, Monkey, Rhesus|
Custom Peptides Service
In the researches of coronavirus COVID-19, customized peptides can also be offered. Elabscience offers synthesis service of different quality and purity range.