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Human IL-27 Antibody Pair Set

E-KAB-0225

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Product Information

Background IL-27,a member of IL-12/IL-23 heterodimeric family of cytokines,has pleiotropic properties that can enhance or limit immune responses. IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types,including T cells,B cells,macrophages,dendritic cells,natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation,and enhances proliferation of naive CD4+T cells and naive B cells. It,however,also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.
Synonyms IL-27, IL-27A, IL27p28, IL30, MGC71873, p28,IL-27B
Swissprot Q8NEV9
Reactivity Human
Usage Detects Human IL-27 in ELISAs
Buffer Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% pro
Storage Store at -20℃. Avoid freeze / thaw cycles.
Expiration Date 12 months
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