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Human IL-29 Antibody Pair Set

E-KAB-0232

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Product Information

Background Cytokine with antiviral,antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense,predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1,and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG),which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Synonyms IFNL1, IL-29, IL29, interferon, lambda 1, interferon lambda 1
Swissprot Q8IU54
Reactivity Human
Usage Detects Human IL-29 in ELISAs
Buffer Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% pro
Storage Store at -20℃. Avoid freeze / thaw cycles.
Expiration Date 12 months
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