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Human TFPI Antibody Pair Set

E-KAB-0215

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Product Information

Background This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization.
Synonyms EPI, LACI, TFI, TFPI1, lipoprotein-associated coagulation inhibitor
Swissprot P10646
Reactivity Human
Usage Detects Human TFPI in ELISAs
Buffer Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% pro
Storage Store at -20℃. Avoid freeze / thaw cycles.
Expiration Date 12 months
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