Recombinant Human ALK-1/ACVRL1 Protein (Fc Tag)
PKSH031899
| Size: | Price: | $670 | |
| Qty: |
-
+
|
Product Details
| Catalog number | PKSH031899 |
| Expression_host | HEK293 Cells |
| Sequence | Met 1-Gln 118 |
| Bio_Activity | 1. Measured by its ability to bind Human ENG-Fc, latent TGFB1-His, mouse ENG-His in functional Elisa. 2. Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombiant human BMP9. |
| Application | Functional ELISA |
| Accession | NP_000011.2 |
| Synonyms | Serine/Threonine-Protein Kinase Receptor R3;SKR3;Activin Receptor-Like Kinase 1;ALK-1;TGF-B Superfamily Receptor Type I;TSR-I;ACVRL1;ACVRLK1;ALK1;HHT;HHT2;ORW2;SKR3 |
| Tag | C-hFc |
| Purity | > 97 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
